1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects

Translational readthrough at F8 nonsense variants in the factor VIII B domain contributes to residual expression and lowers inhibitor association

Modulation of factor VIII pharmacokinetics by genetic components in factor VIII receptors

F9 missense mutations impairing factor IX activation are associated with pleiotropic plasma phenotypes

The Asialoglycoprotein Receptor Minor Subunit Gene Contributes to Pharmacokinetics of Factor VIII Concentrates in Hemophilia A

The p.P1127S pathogenic variant lowers von Willebrand factor levels through higher affinity for the macrophagic scavenger receptor LRP1: Clinical phenotype and pathogenic mechanisms

The Factor VII Variant p.A354V-p.P464Hfs: Clinical versus Intracellular and Biochemical Phenotypes Induced by Chemical Chaperones

Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity

The carboxyl-terminal region of coagulation serine proteases: A matter of cut and change

An exon-specific small nuclear u1 rna (Exspeu1) improves hepatic otc expression in a splicing-defective spf /ash mouse model of ornithine transcarbamylase deficiency

Expression profiles of the internal jugular and saphenous veins: Focus on hemostasis genes

Molecular insights into determinants of translational readthrough and implications for nonsense suppression approaches

An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics

A recoded view on the F9 p.Cys178Ter pathogenic mechanism

Translational readthrough of GLA nonsense mutations suggests dominant-negative effects exerted by the interaction of wild-type and missense variants

An Altered Splicing Registry Explains the Differential ExSpeU1-Mediated Rescue of Splicing Mutations Causing Haemophilia A

Missense changes in the catalytic domain of coagulation factor X account for minimal function preventing a perinatal lethal condition

Disease-causing variants of the conserved+2T of 5 ' splice sites can be rescued by engineered U1snRNAs

The carboxyl-terminal region of human coagulation factor X as a natural linker for fusion strategies

Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca 2+ levels and tumor growth